张鹏,男,药理学博士,硕士研究生导师。湖北省天然药物化学与资源评价重点实验室秘书。主要从事天然生物活性成分的研究以及中药新药的开发。2003-2006年就读于我校同济新葡萄3522登录网页版天然药物化学专业并获博士学位。2007-2008年于我校同济医学院生物化学与分子生物学博士后科研流动站开展博士后研究工作。主持国家自然科学基金1项,参与多项国家和省部级科研项目;申请国家发明专利3项;在国内外重要刊物上发表论文20余篇,其中SCI收录12篇。
1997.09-2001.07 我校同济新葡萄3522登录网页版 药学专业 学士学位
2001.09-2006.07 我校同济新葡萄3522登录网页版 药理学专业 博士学位
2006.08-2009.04 我校同济医学院基础医学院 博士后
2009.04至今 我校同济新葡萄3522登录网页版 天然药物化学专业 讲师
1.2010.01-2012.12:承担国家自然科学基金项目“基于IKB激酶的民族药雪里见抗RA活性成分及作用机制的研究”(项目编号:81001612) 18万
2. 2011.01-2012.12:承担横向项目“标准物质浙贝乙素和湖贝甲素的制备”18万
3.2009.01-2011.12:承担我校人才启动基金项目“民族药雪里见抗RA活性物质基础的研究”5万
4.2006.08-2009.03:担我校博士后基金项目“浙贝乙素胆汁酸衍生物镇咳作用机制的研究”1万
5.2009.01-2011.12:参加国家自然科学基金项目“野核桃青果皮抗肿瘤活性成分及作用机制研究”(项目编号:30873361) 31万
6.2007.01-2009.12:参加国家自然科学基金项目“红活麻负调控DCT-bet,干预RA发病的有效成分研究”(项目编号:30672655) 28万
7.2006.01-2008.12:参加国家自然科学基金项目“民族药忽地笑抗AD的活性成分及机制研究” (项目编号:30572312) 30万
8.2004.01-2006.12:参加国家自然科学基金项目“以IL-18为靶点民族药冷水七抗类风湿性关节炎活性成分及机制研究”(项目编号:30371733) 21万
1. Yang, X.L.,Zhang, P. *, Wu, J.Z., Xiong, S.Q., Jin, N.X., Huang, Z.B. The neuroprotective and lifespan-extension activities of Damnacanthus officinarum extracts in Caenorhabditis elegans. 2012, 141(1): 41-47.(A类期刊)
2. Lu-Jun Li, Yue Zhang,Peng Zhang*, Hui-Fang Pi, Han-Li Ruan and Ji-Zhou Wu. Two new 5,8-quinoflavans from the leaf of Ilex centrochinensis. Journal of Asian Natural Products Research, 13( 4), 2011, 341–345(B类期刊)
3. Lu-Jun Li, Yue Zhang,Peng Zhang*, Hui-Fang Pi, Han-Li Ruan and Ji-Zhou Wu. Flavans from the leaf of Ilex centrochinensis. Journal of Asian Natural Products Research, 13( 4), 2011, 367-372.(B类期刊)
4. Chen Chunxia,Zhang Peng*, Pi Huifang, Ruan Hanli, Hu Zehua,Wu Jizhou. Extracts of Arisaema rhizomatum C.E.C. Fischer attenuate inflammatory response on collagen-induced arthritis in BALB/c mice. Journal of Ethnopharmacology, 133 (2011) 573–582(A类期刊)
5. Yue Zhang, Lu-Jun Li,Peng Zhang*, Hui-Fang Pi, Han-Li Ruan, and Ji-Zhou Wu. Three New E-Secoursane Triterpenoid Saponins from the Leaves of Ilex dunniana. Helvetica Chimica Acta, 94 (2011): 2207–2214(B类期刊)
6. Lujun Li , Yue Zhang,Peng Zhang*, Huifang Pi, Hanli Ruan, Jizhou Wu. Appraisal of anti-inflammatory and free radical scavenging activities of ethanol extract of Ilex ficoidea Hemsl and Ilex centrochinensis S.Y. Hu. Environmental Toxicology and Pharmacology, 32(2), 2011,122-127 (C类期刊)
7. Wu Xiao,Zhang Peng*, Wu Jizhou. Development and validation of a liquid chromatography–mass spectrometry method for the determination of verticinone in rat plasma and its application to pharmacokinetic study[J]. Journal of Chromatography B, 878 (2010) 2067–2071(A类期刊)
8. Xue-Feng Zhou, Lan Tang,Peng Zhang*, Xiao-Ya Zhao, Hui-Fang Pi,Yong-Hui Zhang, Han-Li Ruan, Yonghong Liu, Ji-Zhou Wu. The Interleukin-18 Inhibitory Activities of Echinocystic Acid and its Saponins from Impatiens pritzellii var. hupehensis[J]. Z. Naturforsch. 2009(64):369 – 372.(C类期刊)
9. Xue-Feng Zhou,Peng Zhang*, Hui-Fang Pi, Yong-Hui Zhang, Han-Li Ruan, Hui Wang, Ji-Zhou Wu. Triterpenoids from the Roots of Actinidia chinensis[J]. CHEMISTRY & BIODIVERSITY, 2009(6): 1202-1207.(B类期刊)
10. Zhang JL, Wang H, Chen C, Pi HF, Raun HL,Zhang P*, Wu JZ.Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor[J]. Acta Pharmacol Sin. 2009 May;30(5):559-66(B类期刊)
11. Zhou Huan, Yue Pei, Ruan Hanli, Zhang Yonghui, Pi Huifang,Zhang Peng*and Wu Jizhou. Microwave-Promoted Rearrangement of Hecogenin Derivatives into Cnor-D-homo Steroids[J]. Letters in Organic Chemistry, 2009, 6(2): 126-129(C类期刊)
12.Peng ZHANG, Juan LI, Guo-xin Zhang, Ji-zhou WU. Analysis of Hupehenine in the Total Alkaloids from Fritillaria hupehensis by HPLC-ELSD[J]. Journal of Huazhong University of Science and Technology [Med Sci ] 2008 (1):118-120(C类期刊)
13. 用于预防或治疗痴呆症的组合物(国家发明专利申请号:200910061169.7)
14. 浙贝乙素胆汁酸酯及其制备方法和应用(国家发明专利申请号:200810048722.9)
15.张鹏,皮慧芳,张久亮,阮汉利,张勇慧,吴继洲.湖北贝母茎叶中的生物碱成分的研究[J]. 中草药, 2008, 39(9):1294-1296
16.张鹏,周伟,陈霞,皮慧芳,阮汉利,吴继洲.顶空气相色谱法测定湖北贝母提取物中的大孔吸附树脂残留物[J].中国医院药学杂志, 2009,29(4)
17.张鹏,李娟,张国欣,吴继洲。大孔吸附树脂分离纯化湖北贝母总生物碱的研究[J],中成药,2007,29(1):51-54
18.张鹏,阮汉利,张勇慧,皮慧芳,吴继洲。紫花鄂北贝母非生物碱成分的化学研究[J],中草药,2005,36(9):1304-1306
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