国家自然科学基金面上项目,81973257,在研,参加
近几年部分研究成果:
(1) Yannan Yang#, Yao Lu #, et al. Stepwise degradable nanocarriers enabled cascade delivery for synergistic cancer therapy. Advanced Functional Materials, (2018), 28: 1800706. (共同第一作者) (IF=15.621)
(2) Yao Lu#, Yannan Yang#, et al. Glutathione-Depletion Mesoporous Organosilica Nanoparticles as a Self-Adjuvant and Co-delivery Platform for Enhanced Cancer Immunotherapy. Biomaterials. 2018,82-92. (IF= 10.273)
(3) Hao Song, Meihua Yu, Yao Lu, Zhengying Gu, et al. Plasmid DNA Delivery: Nanotopography Matters, Journal of the American Chemical Society, 2017, 139(50): 18247-18254. (IF=14.695)
(4) Yannan Yang#, Yao Lu#, Prasanna Lakshmi Abbaraju, et al. Multi‐shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy, Angewandte Chemie, 2017, 129(29): 8566-8570 (共同第一作者) (IF=12.257)
(5) Yao Lu, Yuhua Wang, Lei Miao, Matthew Haynes, et al. Exploiting in situ antigen generation and immune modulation to enhance chemotherapy response in advanced melanoma: a combination nanomedicine approach, Cancer letters, 2016, 379(1): 32-38. (IF=6.508)
(6) Yao Lu, Lei Miao, Yuhua Wang, Zhenghong Xu, et al. Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model. Molecular Therapy. 2016. 24(2): 364-374 (IF=8.402)
(7) Yao Lu#, Nan Ding#, Chang Yang, Lei Huang L, Jian Liu, Guangya Xiang. Preparation and in vitro Evaluation of a Folate-Linked Liposomal Curcumin Formulation. Journal of Liposome Research. 2012, 22, 110-119.
(8) Nan Ding#,Yao Lu#, Robert J Lee#, Chang Yang, Lei Huang, Jian Liu, Guangya Xiang,Folate receptor targeted fluorescent paramagnetic bimodal liposomes for tumor imaging, International Journal of Nanomedicine,2011,6:2513-2520 (共同第一作者)
(9) Peng Ye, Wendian Zhang, Tan Yang, Yao Lu, Mao Lu, Yongkang Gai, Xiang Ma, Guangya Xiang. Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting. International Journal of Nanomedicine. 2014, 9, 2167-2178.