斯陆勤，女，副教授，硕士研究生导师，自2001年起一直在我校同济新葡萄3522登录网页版药剂教研室从事药剂学、生物药剂学与药动学以及临床药动学的教学与科研工作。目前为湖北省药学会药物制剂专业委员会委员、湖北省药品注册现场核查员等。主持国家自然科学基金1项，湖北省科技攻关计划项目和湖北省卫生厅项目各1项，参与科技部国家重大新药创制项目2项、国家863课题1项，国家自然科学基金3项，省部级课题多项，并承担多项药物新制剂开发、药物动力学及制剂生物等效性相关的横向课题。已发表学术论文50多篇，其中SCI收录论文16篇，申请发明专利7项，获授权2项。
2009.11-我校同济医学院新葡萄3522登录网页版药学系，副教授
2011.10-2012.10 University of Toronto, Leslie Dan Faculty of Pharmacy国家公派访问学者（博士后）
2003.9-2009.10我校同济医学院新葡萄3522登录网页版药学系，讲师
2001.9-2003.8我校同济医学院新葡萄3522登录网页版药学系，助教
1）新型肾上腺素受体和受体双重阻断药物-TJ0711的研发，国家科技部重大专项（2009ZX09103-146，2012ZX09102101-016），第二
2）VP16纳米粒对肝药酶功能的影响及作用机制研究,我校自主创新前沿探索项目，主持
3）药用辅料促进肠道pept1转运作用及其机理研究，国家自然科学基金（30903025），主持
4）具有P-gp药泵/CYP3A药酶双重抑制作用的促口服吸收载药系统的构建与机制研究，国家自然科学基金（30873171）
5）IBL胶囊剂的研发（3.1类）.企业课题，主持
6）VIN滴眼剂的研究.武汉新药创制平台项目.主持
[1]Gang Zhao,Jiangeng Huang,Kewen Xue,Luqin Si*,Gao Li. Enhanced intestinal absorption of etoposide by self-microemulsifying drug delivery systems: roles of P-glycoprotein and cytochrome P450 3A inhibition.Eur J Pharm Sci,.2013; 20; 50(3-4):429-39.
[2] Jiangeng Huang, Lei Hu, Li Xu, Minghui Sun, Zhaoze Fan, Jun Qiu, Gao Li,Luqin Si *. In vitro enantioselective metabolism of TJ0711 hydrochloride by human liver microsomes using a novel chiral liquid chromatography-tandem mass spectrometry method.J Chromatogr B Analyt Technol Biomed Life Sci.2012; 891-892:98-101.
[3] Minghui Sun, Xuezhen Zhai, Kewen Xue, Lei Hu, Xiangliang Yang, Gao Li,Luqin Si *. Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation with oral bioavailabilities in rats. Eur J Pharm Sci, 2011; 14;43(3):132-40.
[4] Jiangeng Huang,Luqin Si, Zhaoze Fan, Lei Hu, Jun Qiu, Gao Li*. In vitro metabolic stability and metabolite profiling of TJ0711 hydrochloride, a newly developed vasodilatory β-blocker, using a liquid chromatography-tandem mass spectrometry method.J Chromatogr B Analyt Technol Biomed Life Sci,2011;879(30):3386-92.
[5] AK Rabba,Luqin Si, Kewen Xue, Ming Li, Gao Li*.In Situintestinal perfusion of irinotecan: application to P-gp mediated drug interaction and introduction of an improved HPLC assay.J Pharm Pharm Sci,2011;14(2):138-47.
[6] Minghui Sun,Luqin Si, Xuezhen Zhai, Zhaoze Fan, Yiming Ma, Rui Zhang, Xiangliang Yang*. The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems.Drug Dev Ind Pharm,2011;37(8):986-94. [6] Guan Yanbin, Huang Jiangeng, Zuo Lan, Xu Jiaqiang,Si Luqin, Qiu Jun, Li Gao. Effect of pluronic P123 and F127 block copolymer on P-glycoprotein transport and CYP3A metabolism.Arch Pharm Res,2011;34(10): 1719-28.
[7] Ming Li,Luqin Si, Hongping Pan, AK Rabba, Fang Yan, Jun Qiu, Gao Li. Excipients enhance intestinal absorption of ganciclovir by P-gp inhibition: assessedin vitroby everted gut sac andin situby improved intestinal perfusion.Int J Pharm, 2011;403(1-2): 37-45.
[8]Yanbin Guan,Jiangeng Huang,Lan Zuo, Jiaqiang Xu,Luqin Si, Jun Qiu, Gao Li*. Effect of pluronic P123 and F127 block copolymer on P-glycoprotein transport and CYP3A metabolism.Arch Pharm Res.2011,34(10):1719-1728.
[9] Zhaoze Fan,Luqin Si *, Li Xu, Yiming Ma, Le Hu i, Jun Qiu, Gao Li*. Determination of TJ0711 hydrochloride in rat plasma by high performance liquid chromatography with fluorescence detection and its application to pharmacokinetics.J Chromatogr B Analyt Technol Biomed Life Sci,2010;878(22): 2035-2038.
[10] Zichao Rao,Luqin Si, Yanbin Guan, Hongping Pan, Jun Qiu, Gao Li*. Inhibitive effect of cremophor RH40 or tween 80-based self-microemulsiflying drug delivery system on cytochrome P450 3A enzymes in murine hepatocytes.J Huazhong Univ Sci Technolog Med Sci,
[11] Sun Shuping,Si Luqin, Fan Zhaoze, Qiu Jun, Li Gao. Stereoselective HPLC assay of TJ0711 enantiomers by precolumn derivatization with GITC using UV detection and its application in pharmacokinetics in rats.J Huazhong Univ Sci Technol [Med Sci], 2009;29(4): 427-430.
[12]Luqin Si, Ying Zhao, Sha Li, Xuezhen Zhai, Gao Li*. Calcium pectinate gel bead intended for oral protein delivery: preparation improvement and formulation development.Chem Pharm Bull,2009;57(7): 663-667.
[13] Xiuhua Ren, Xinliang Mao, Lei Cao, Kewen Xue,Luqin Si *, Jun Qiu, D Aaron. Schimmer and Gao Li. Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo.Eur J Pharm Sci ,2009;36(4-5): 401-411.
[14]LuqinSi,Ying Zhao,Jiangeng Huang, Sha Li, Xuezhen Zhai, Gao Li. Calcium pectinate gel bead intended for oral protein delivery: preparation improvement and formulation development.Chem Pharm Bull.2009; 57(7):663-667.
[16]Jiangeng Huang,Luqin Si, Lingli Jiang, Zhaoze Fan, Jun Qiu, Gao Li*. Effect of pluronic F68 block copolymer on P-glycoprotein transport and CYP3A4 metabolism.Int J Pharm；2008; 356(1-2):351-353.
《药剂学》（高等院校药学与制药工程专业规划教材）浙江大学出版社.2010.1，参编
《药剂学》（全国普通高等专科教育药学类规划教材）中国医药科技出版社.2012.7，参编
《实用药学计算》化学工业出版社.2007.3，参编
陈鹰,李高,汤韧,斯陆勤,符旭东,杜蓉,张宜,刘辉,何艳,孙明辉.新型自微乳释药技术改善难溶性药物溶解和吸收特性的研究.2012年度湖北省科技进步二等奖.
2009年获我校同济新葡萄3522登录网页版‘葛店人福杯’青年教师讲课比赛二等奖
[1]斯陆勤;李高;赵瑛;黄建耿. 喷滴法微球制备装置.（ZL200820230402.0）
[2]李高;孙淑萍;陈邦银;斯陆勤;裘军;范昭泽.一种新型抗高血压化合物的光学对映体的制备.（ZL200810236898.7）
[3]陈邦银;李高;裘军;斯陆勤;孙淑萍.一种抗高血压化合物及其制备方法.（公开号：CN101508652）
[4]李高;斯陆勤;胡彬;黄建耿.尼美舒利-羟丙基-b-环糊精包合物滴眼剂及其制备方法.(公开号：CN101433721）
[5]李高;郭伟林;斯陆勤;黄建耿;胡磊;胡洋.一种a/b受体双重抑制剂缓释片及其制备方法.（公开号：CN102579380A）
[6]李高;胡磊;陈邦银;裘军;斯陆勤;黄建耿;苏玉永.一种a/b受体双重抑制剂及其盐的制备方法.（公开号：CN102617368A）
[7]李高;陈鹰;斯陆勤;黄建耿.长春西汀口服自微乳化释药系统及其制备方法.（公开号：CN101103962）
通信方式：湖北省武汉市航空路13号 我校同济医学院新葡萄3522登录网页版 430030
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